Congratulations to Pauline Favre, newly recruited as a research fellow at Inserm in Marion Leboyer’s team!

Pauline Favre is a neuropsychologist, recently recruited at INSERM as a CRCN researcher in Marion Leboyer’s team “Neuropsychiatrie Translationnelle”.

She did her PhD in Psychology, Cognitive Sciences and Neurocognition at the University of Grenoble (LPNC – CNRS) on the brain correlates of bipolar disorder and the contribution of psychoeducation in the treatment of this disorder. Since then, she has been developing research on the neuroimaging of psychiatric disorders and the development of new therapeutic interventions.

After a 2-year postdoctoral stay at the Max Planck Institute in Leipzig, Germany, where she worked on the impact of meditation training on emotional brain reactivity, she joined the methodological unit of the Neuroimaging platform Neurospin at CEA Saclay. Since then, she has been involved in the study of large international neuroimaging cohorts of psychiatric disorders, such as those of the ENIGMA consortium, using artificial intelligence (machine learning).

For the past 3 years, she has been pursuing her research within the Inserm laboratory “Neuro-Psychiatrie Translationnelle” (Marion Leboyer team), the IMRB and in collaboration with the Neuroimaging platform Neurospin. His current work focuses on a better understanding of the pathophysiology of mood disorders; a redefinition of these disorders with the contribution of large cohorts and artificial intelligence; and the development of innovative therapies, such as neurofeedback in functional MRI.

Since 2019, she has been developing a clinical research project on the use of functional MRI neurofeedback for the treatment of residual depressive disorders in patients with bipolar disorder. This project is funded by the National Collaborative Hospital Research Program (PHRC-N).

Major publications :

– Favre, P., Pauling, M., Stout, J., Hozer, F., Sarrazin, S., Abé, C., Alda, M., Alloza, C., Alonso-Lana, S., Andreassen, O.A., Baune, B.T., […], Leboyer, M., Mangin, J-F, Henry, C., Duchesnay, E. & Houenou, J. (2019). Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega-and meta-analyses across 3033 individuals. Neuropsychopharmacology, 44(13), 2285-2293.
– Favre, P., Houenou, J., Baciu, M., Pichat, C., Bougerol, T. & Polosan, M. (2016). White-matter plasticity induced by psychoeducation in bipolar patients: A controlled diffusion tensor imaging study. Psychotherapy and Psychosomatics, 85, 58-60.
– Favre, P., Baciu, M., Pichat, C., Bougerol, T. & Polosan, M. (2014). FMRI evidence for abnormal resting-state functional connectivity in euthymic bipolar patients. Journal of affective disorders, 165, 182-189.
– Favre, P., Kanske, P., Engen, H., Singer, T. (2021). Decreased emotional reactivity after 3-month socio-affective but not attention- or meta-cognitive-based mental training: A randomized, controlled, longitudinal fMRI study. NeuroImage 237, 118132.