Dernières actualités de l’équipe
The team is now operational in the fully renovated faculty Building 4th floor
The team is getting up to speed with the new Novocyte Opteon spectral cytometer by Agilent.
Ana Carolina VALENTE DE ARAUJO coming from Brasil has just joined the team for one year to learn more on spectral cytometry and 2-photon imaging
Congratulations to Thomas PELÉ for his recruitment as a study Engeneer at Inserm. He will join the team starting February 2026.
Thème de recherche :
The STORM-MI team at the Mondor Institute for Biomedical Research focuses on understanding how environmental stresses—including infectious diseases, chemical and physical pollutants, cancer, and aging—reshape the mononuclear phagocyte system (MPS), a central regulator of tissue integrity and immune homeostasis. By combining advanced in vivo imaging, spatial and single cell genomic, genetic and epigenetic analyses, and the study of extracellular vesicle–mediated communication, the team investigates how monocytes and tissue-resident macrophages sense and respond to local perturbations within their tissue niches. This integrated approach merges state-of-the-art mechanistic research in innovative murine models with strong clinical partnerships in hematology, oncology, urology, and emergency medicine, enabling the translation of discoveries to human biology. STORM-MI aims to identify novel biomarkers of disease progression, therapeutic resistance, and immune dysregulation, while uncovering molecular pathways that drive myeloid cell dysfunction in hematologic malignancies, solid tumors and in response to external insults. Ultimately, the team seeks to leverage these insights to design new immunomodulatory strategies capable of restoring effective myeloid responses and improving clinical outcomes.
